由于佐剂具有其自身的药理学特性，可能会影响疫苗的免疫原性和安全性，因此对其进行安全性评估是必不可少的。

Since adjuvants have their own pharmacological properties, which might affect both the immunogenicity and the safety of vaccines, safety assessment is essential.

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本文综述了右旋美托咪啶的药理学、药物代谢动力学及其在重症监护病室中的临床应用，包括对谵妄的防治、药物本身的安全性和其特殊的可唤醒镇静效应。

This article reviewed the pharmacology, pharmacokinetics and its application in ICU, including its application in prevention and control of delirium, drug safety and its arousal sedation effects.

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