...用_中药学_医药卫生_论文宝库 nic constriction injury of the sciatic nerve, CCI)模型及大鼠脊神经结扎(spinal nerve ligation,SNL)模型上,探讨钩吻素子对神经病理性疼痛的治疗作用,为其进一步研发成新型的治疗NPP药物提供临床前药效学..
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...药学_医药卫生_论文宝库 nic constriction injury of the sciatic nerve, CCI)模型及大鼠脊神经结扎(spinal nerve ligation,SNL)模型上,探讨钩吻素子对神经病理性疼痛的治疗作用,为其进一步研发成新型的治疗NPP药物提供临床前药效学..
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模型及大鼠脊神经结扎 spinal nerve ligation ; SNL
目的：研究L5脊神经结扎模型大鼠脊髓星形胶质细胞的激活与痛行为之间的关系。
Objective: To investigate the relationship between the spinal astrocytic activation and neuropathic pain behavior in L5 spinal nerve ligation (SNL) rats.
方法：以L 5脊神经结扎制备大鼠神经病理性痛模型，利用分离背根单纤维细胞外电生理记录异位放电。
Methods: Using L5 spinal nerve ligation as neuropathic pain model of rats, teased fiber recording technique was used to explore the property of ectopic discharges.
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