目的观察重组大鼠肝再生增强因子(alr)对肝星状细胞株ig12增殖及细胞外基质合成的影响,探讨其抗肝纤维化作用的可能机制。
Objective To observe the effects of recombinant augmenter of liver regeneration (ALR) on the proliferation of hepatic stellate cell line IG12 and ECM synthesis.
结论从2周龄大鼠肝组织中成功克隆肝再生增强因子基因,并获得了原核细胞高效表达。
ConclusionThe augementer of liver regeneration gene was cloned from the liver tissue of 2 week old SD rat and the protein encoded by the gene was expressed in the prokaryotic cells.
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