...灵; 单侧输尿管阻塞; 间质纤维化; 摘要: 目的 探讨中药复方抗纤灵治疗大鼠单侧输尿管结扎(unilateral ureteral obstruction,UUO)所致肾纤维化的作用及机理.方法 雄性SD.
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在本研究中我们运用大鼠单侧输尿管结扎术(unilateral ureteral obstruction, UUO)建立肾间质纤维化模型,用苦参山楂合剂灌胃,通过观察肾间质病理变化及测定CTGF、α平滑肌肌动蛋白(...
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大鼠单侧输尿管结扎术 unilateral ureteral obstruction
目的:探讨中药抗纤灵方对大鼠单侧输尿管结扎(UUO)所致肾纤维化的防治作用及机制。
Objective: To study the effects of "Kangxian Ling Decoction" (KLD) on renal interstitial fibrosis induced by unilateral ureteral obstruction (UUO) in rats.
目的证实结扎致单侧输尿管梗阻(uuo)大鼠模型梗阻侧肾脏是否存在低氧,不同时间点低氧的特点及低氧与肾间质纤维化的关系。
Purpose To observe whether hypoxia exists in the obstructed kidney of unilateral ureteral obstruction (UUO) rat model and its distribution relationship with tubulointerstitial fibrosis.
方法:将大鼠随机分为单侧输尿管结扎试验组和假手术对照组。
METHODS: The rats were randomly divided into unilateral ureteral ligation Testing Group and sham operation Control Group.
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