结果我们研制的芯片能同时特异性地检测耐药相关单一或多位点突变。

Results The microarray can identify a single base change of selected lamivudine resistance-related mutation and multiple mutation detection by a single assay as well.

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结果发现，在24名治疗前KRAS为野生型的患者中有9名(38%)患者的血清检测出突变型KRAS。其中3名的突变为多位点的不同突变。

We found that 9 out of 24 (38%) patients whose tumours were initially KRAS wild type developed detectable mutations in KRAS in their sera, three of which developed multiple different KRAS mutations.

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