低氧可激活低氧诱导因子(HIF - 1),从而调控一系列与缺氧相关基因的表达。
Hypoxia activates hypoxia-inducible factor 1 (HIF-1), thus it controls a series of expression of genes correlated with hypoxia.
目的:头叉转录因子箱(FOXP3)---调控大量基因的表达而且有报道说已在肿瘤细胞中有表达。
Purpose: The transcription factor forkhead box P3 (FOXP3) up- or down regulates a large number of genes and has been recently reported to be expressed in tumor cells.
基因表达是由众多顺式作用元件和反式作用因子相互作用调控的。
Gene expression is regulated by the complex interaction of many cis-acting elements and trans-acting factors.
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