Martin和Torres-Aleman(2008)在研究中使用一种低血清IGFI水平的肝脏IGFI基因缺陷小鼠(livet-IGF-I deficient，LID)，发现运动及抗抑郁药物在诱导正常小鼠海马神经发生的同时能够提高小鼠在FST测试中的表现；相反，运动却
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目的观察我部饲养的不同年龄、不同性别的载脂蛋白E基因缺陷小鼠的血脂及病理组织学状况。
Objective Serum lipid and histopathological status were observed in apoE gene knockout mice of different genders and ages.
一些小鼠还有肿瘤抑制基因p 53缺陷，这种缺陷突变存在与大约一半的人类肺癌。
Some of the mice also had defective versions of the tumor suppressor gene p53, which is mutated in about half of human lung cancers.
最近的研究表明，COX-2基因敲除小鼠的生殖缺陷主要依赖小鼠的遗传背景，与小鼠的品系相关。
However, it was recently shown that the reproductive defects of COX-2-deficient mice mainly depend upon genetic background of the mouse strains.
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