...毒使用频率最低的密码子,全基因合成NS基因,利用12质粒反向遗传操作技术拯救出含有密码子去优化NS1基因的重组病毒(deoptimized NS, deoNS)。
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后来,来自美国哈佛大学的科学家证明,通过使老鼠的胰腺细胞感染上只携带三个转录因子的基因病毒,能将其重组。
Later, scientists from Harvard University in the us showed that mouse pancreas cells could be reprogrammed by infecting them with viruses carrying genes for just three transcription factors.
但是让人感到恐惧的是,H5N1可以与更容易对人类造成感染的流感病毒交换基因片段(重组)而得到进化。
One fear, however, is that H5N1 might become better at infecting humans by swapping genetic parts (reassortment) with types of flu virus that already infect humans easily.
所有八个基因片断的排序未发现证据表明与人或猪的流感病毒发生基因重组,也无证据表明发生显著突变。
Sequencing of all eight gene segments found no evidence of genetic reassortment with human or pig influenza viruses and no evidence of significant mutations.
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