糖皮质激素是垂体-下丘脑-肾上腺（hypothalamic-pituitary-adrenal，HPA）轴的最终激素，受神经内分泌系统的精细调节，又可作用于许多靶组织，发挥重要作用。
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这些受体可以控制下丘脑-垂体-肾上腺（HPA）轴的活性，HPA轴是一个对应激产生反应的内分泌系统。
These receptors control the activity of the hypothalamo-pituitary adrenal (HPA) axis, an endocrine system that is activated in response to stress.
此激素的反馈循环被称为下丘脑-垂体-肾上腺轴心。
This hormonal feedback loop is referred to as the hypothalamic-pituitary-adrenal axis HPA.
目的：了解2型糖尿病患者和2型糖尿病伴发抑郁症患者的下丘脑-垂体-肾上腺轴（HPA）变化及其临床意义。
Objective:To investigate the variations of hypothalamus pituitary adrenal axis(HPA) in type 2 diabetic patients and those with depression and to evaluate their clinic significance.
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