大量事实表明，包括脑肿瘤在内，所有肿瘤细胞群落之间在形态和功能上存在很大差异，其异质性与肿瘤干细胞的分化潜能有关。

There is overwhelming evidence that the tumor clone including brain tumor is heterogeneous with respect to both morphology and function, which indicates differentiation potential of tumor stem cells.

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目的：探讨卡莫司汀对人脑肿瘤干细胞在细胞增殖及细胞周期方面的影响。

Objective To investigate the effects of BCNU on the proliferation and cell cycle of stem cells from human brain tumor.

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目的探讨脑肿瘤干细胞(BTSC)在体外分化过程中的细胞形态、分化相关标志物表达和增殖动力学变化，为进一步研究BTSC分化走向提供实验依据。

Objective To pursue the changes of cell morphology, expression of differentiation related markers, and proliferation cycles of brain tumor stem cells (BTSCs) after differentiation in vitro.

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