...已有研究表明Wnt/β-catenin信号途径调节高糖诱导的肾小球系膜细胞凋亡过程,在单侧输尿管梗阻(Unilateral Ureteral Obstruction,UUO)肾脏该途径表达上调,提示此途径可能参与了慢性肾脏病的发病。
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目的探讨雌激素在单侧输尿管梗阻（UUO）大鼠肾间质纤维化模型中对肾小管上皮细胞表型转化的影响。
To evaluate the effect of estrogen on tubular epithelial cell phenotype transdifferentiation of tubulointerstitial fibrosis in unilateral ureteral obstruction(UUO)rats.
目的：动态观察P 21在单侧输尿管梗阻肾间质纤维化大鼠模型中的表达，以及依那普利对其表达的调节。
Objective To investigate the expression of P21 in renal interstitial fibrosis rats and the effect of enalapril on it.
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