...ncer; phage displayed peptide library; angiogenesis; peptides; structure modeling [gap=444]关键词】 胃癌;噬菌体随机肽库;血管生成;多肽;结构模拟 ...
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...区特异性结合肽的筛选目的:以人工合成的钠泵α1亚基M1-M2膜外区蛋白为靶标,通过 噬菌体随机肽库 ( phage random peptide library )技术筛选能与之特异性结合的多肽,以阻断或拮抗哇巴因对钠泵的抑制作用,为进一步探讨钠泵与其抑制因子的可能作用机制及高血压的治...
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结论：丝状噬菌体随机肽库被成功构建。
Conclusion: The random peptide library has been successfully constructed.
方法：以甲三型流感病毒裂解疫苗原液为靶分子，经过3轮生物淘选，从噬菌体随机肽库中筛选与之结合的噬菌体。
Methods: Using the influenza A3 split vaccine as the target molecule, peptides that could bind with target molecule were selected from the phage display 12 peptide library by 3 rounds of biopaning.
同时，本研究所采用的方法也为使用噬菌体随机肽库进行甾体类激素特异性受体（配体）的筛选提供了可靠的实验依据。
The results also show that phage display peptide library is an effective, simple and efficient method to select specific steroid receptors.
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