...水平的调控是基因调控的重要环节,其中转录因子(Transcription Factor,TF)和转录因子结合位点(Transcription Factor Binding Site,TFBS)是转录调控的重要组成部分.
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目的:预测人类BMP - 2基因启动子位置和可能的转录因子结合位点。
Objective: to predict the promotor position and transcription factor binding sites of human BMP-2 gene.
目前,已经有大量的方法用于识别转录因子结合位点,大致可分为基于保守模体和比较基因组学两种方法。
There are a large number of methods for identifying transcription factor binding sites, and it can be divided into two ways: conservative motif based and comparative genomics.
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