...及其初步应用 溶液作标准曲线 5.2.4微球的载药量(drug loading efficiency，dle)和药物的包封率(drug entrapment efficiency，dee)的测定 5.2.5载药微球的处理 5.2.6裸鼠人胃癌肿瘤模型的建立 5.2.7磁性聚n..
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...初步应用 溶液作标准曲线 5.2.4微球的载药量(drug loading efficiency，dle)和药物的包封率(drug entrapment efficiency，dee)的测定 5.2.5载药微球的处理 5.2.6裸鼠人胃癌肿瘤模型的建立 5.2.7磁性聚n..
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方法：以包封率和平均粒径为评价指标，采用星点设计-效应面法优化醇质体处方中大豆磷脂、药物和无水乙醇的最佳配比。
METHODS Taking encapsulated ratio and average diameter as evaluation index to optimize the best matching of soybean phospholipid, drug and absolute alcohol in ethosomes.
结果：通过调节药物浓度和不同高分子组合筛选出突释小，包封率高且缓慢释放的处方。
Results: By adjusting LDME concentration and different polymer combinations, we achieved microspheres with high encapsulation efficiency, low initial burst and sustained release.
利用扫描电镜和紫外光谱考察了内相聚合物浓度和搅拌速度对微球粒径和药物包封率的影响。
The effects of polymer concentration and agitation rates on the size of microspheres and drug incorporation efficiency were studied by scanning electronic microscopy (SEM) and UV-spectrophotometry.
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