...心医苑网 部位存在着肿瘤浸润淋巴细胞(tumor infiltrating lymphocytes, TIL)和肿瘤相关巨噬细胞(tumor associated macrophages, TAM)，他们在机体肿瘤免疫监视功能方面起着重要作用。
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目的研究壳寡糖对小鼠肿瘤生长和转移的抑制作用以及壳寡糖对培养的巨噬细胞相关的细胞因子表达的影响。
Objective to study the influence of oligochitosan in inhibiting growth and metastasis of tumor in rats, and in expression of cytokines associated with macrophage.
目的探讨脂多糖(LPS)、巨噬细胞表达肿瘤坏死因子相关凋亡诱导配体(TRAIL)和肝细胞凋亡的相互关系。
Objective to investigate the influence of lipopolysaccharide (LPS) on macrophages expressing TNF-alpha related apoptosis induced-ligand (TRAIL) and its relation to apoptosis of HepG2 cell line.
结论壳寡糖具有良好抑制肿瘤生长和转移的作用。壳寡糖可增强巨噬细胞相关的细胞因子表达。
Conclusion Oligochitosan can inhibit growth and metastasis of tumor, and enhance expression of cytokines associated with macrophage.
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