...学与临床 激活后APP蛋白的表达及组蛋白乙酰化酶(Histone Acetyltranferase, HAT)和组蛋白去乙酰化酶(Histone Deacetyltranferase, HDAC)的表达情况；光密度值法检测组蛋白H3和H4整体乙酰化水平。
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医疗_健康_保健_疾病_ppt文档知识 - Part 692 表面,受多种酶催化修饰.组蛋白乙酰转移酶(histoneacetyltransferase,HAT)和组蛋白去乙酰化酶(histonedeacetylase,HDA)是调节组蛋白乙酰化状态的一组酶,与甲基化酶、磷酸化酶等共同完成对组蛋白的翻译后修饰.此外,越来越多的
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靶向DNA甲基化和组蛋白去乙酰化酶的几个表观药物已经在临床试验中被测试。
Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials.
组蛋白乙酰化和去乙酰化由一对功能相互拮抗的蛋白酶——组蛋白乙酰基转移酶和组蛋白去乙酰化酶负责。
The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other, which are histone transacetylase and histone deacetylase.
组蛋白乙酰转移酶和组蛋白去乙酰酶活性共同决定了组蛋白的乙酰化水平。
The level of his-tone acetylation is determined by the activities of histone acetyltransferases and histone deacetylases.
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