在神经发生和早期大脑发育过程中，外切核苷酸酶通常下调嘌呤能信号传导。

During neurogenesis and in early brain development, ectonucleotidases often downregulate purinergic signalling.

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异丁司特作为一种神经胶质激活和环核苷酸磷酸二酯酶抑制剂，已被显示有治疗神经性疼痛和阿片脱瘾的可能性。

Ibudilast, an inhibitor of glial activation and cyclic nucleotide phosphodiesterases, has shown potential in the treatment of neuropathic pain and opioid withdrawal.

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本实验采用还原型尼克酰胺腺嘌呤二核苷酸脱氢酶（NADPH- d）方法，观察扬子鳄食管颈段NOS阳性神经元和神经纤维的分布。

NADPH-diaphorase histochemistry was used to study the distribution of NOS-positive neurons and in the cervical esophagus in Alligator Sinensis.

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