As for Pyranones compounds, the 4-hydroxyl group , the lactone moiety and the branches at C-3 and C-6 position are the active sites.
对吡喃酮类化合物,环上的内酯和羟基,C-3和C-6的支链是化合物的活性区域。
参考来源 - HEPT类和吡喃酮类抗HIV化合物的量子化学与定量构效关系研究·2,447,543篇论文数据,部分数据来源于NoteExpress
吡喃酮类化合物在飞蓬属植物中广泛存并且显示了强的治疗脑中风及调节血压的作用,以及对缺血再灌注损伤的保护作用。
Pyran Derivatives is widespread in erigeron, And the treatment showed a strong stroke, And the regulation of blood pressure, the protection effect For ischemia-reperfusion injury.
目的根据具有趋骨性的化合物的共同特征,设计并合成苯并吡喃4酮类化合物,检测它们的趋骨性。
Aim to design and synthesize benzopyran-4-one derivatives according to the common structural properties of compounds which have bone affinity and test their bone affinity.
应用推荐