目的:研究心脏结构和功能改变与心脏受体自身抗体产生的关系。
AIM: to determine whether the cardiac structural and functional changes are related to the genesis of cardiac receptor auto-antibodies (auto-Ab).
观察抗AT1受体自身抗体阳性的糖尿病合并高血压心功能不全患者缬沙坦靶向治疗对心功能的疗效。
To investigate the effects of Valsartan on the positive AT1 receptor in patients cardiac failure with the diabetes mellitus and hypertension.
由于人类细胞通常不会对自身细胞成分产生抗体,所以科隆诺将人类细胞注射到小鼠体内,小鼠确实会产生对普通受体的抗体。
Because human cells normally do not develop antibodies to components of their own cells, Colonno injected human cells into mice, which did produce an antibody to the common receptor.
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