目的：观察甲氨喋呤(MTX)联合米非司酮连续用药保守治疗异位妊娠的疗效及安全性。

Objective: to observe the curative effect and security of continue application of mifepristone combined with MTX on ectopic gestation.

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结论：RA患者存在焦虑、抑郁情感障碍，RA抑郁的发生可能与个性内倾、功能障碍及长期使用甲氨喋呤有关。

Conclusion: ra patients might have anxiety and depression, the development of depression in ra patients was associated with introversion, disability or MTX therapy.

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椎管内常用的药物有甲氨喋呤及阿糖胞苷。

Intraspinal commonly used drug methotrexate and cytarabine.

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