目的探讨替米沙坦和雷米普利单用或联合用药的降压作用及对心脏功能的影响。
Objective To study the antihypertensive efficacy and effect of combined therapy with Telmisartan and Ramipril on cardiac function of the patients with hypertension.
结果未加及加入氢氯噻嗪后的替米沙坦的蛋白结合率分别为93 8%和94 1%。
Results The protein-binding rate of telmisartan to BSA was 93.8% and 94.1% respectively when incubated without and with hydrochlorothiazide.
国内外有关替米沙坦的研究集中在药理药效研究等方面，对其及中间体的合成的研究报导较少。
The studies on telmisartan focus on pharmacology and efficacy at home and abroad, while the study about it's synthesis has only received few attension.
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