切断主动脉弓和颈动脉窦压力感受器的传入神经,称为去窦弓神经(sinoaortic denervation,SAD),SAD后大鼠血压波动明显[1]。
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大鼠去窦弓神经(sinoaortic-denervated,SAD)可引起BPV明显增高,但24小时平均动脉血压并不增加。SAD大鼠有左心室肥厚及血.
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Subsequently, series of studies were launched on the basis of sinoaortic denervation rat model which has only the simple BPV increased(not accompanied by sustained high blood pressure).
随后,在确认去窦弓神经大鼠为单纯性BPV升高(不伴有持续高血压)动物模型基础上展开研究。
参考来源 - 遥控测压技术应用和血压波动性遗传学研究·2,447,543篇论文数据，部分数据来源于NoteExpress
目的：观察芎归滴丸对选择性去窦弓神经大鼠动脉压力感受反射敏感性的影响。
OBJECTIVE:To observe the effect of Xionggui dripping pills on sensitivity of baroreflex in selective sinoaortic denervated rats.
目的：研究新型AT_1受体拮抗剂坎替沙坦对大鼠去窦弓神经（SAD）引起的心血管肥大的作用及其可能机制。
AIM: To study the effect of candesartan cilexetil (candesartan), a new AT1 receptor antagonist, on sinoaortic denervation (SAD)-induced cardiovascular hypertrophy and its potential mechanisms in rats.
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