毒性实验存在随机误差，同时剂量-效应曲线（DRC）拟合也会产生误差。
Random error exists not only in toxicity experiments but also in the fitting of dose-response curves(DRC).
由于剂量率的影响，利用微核剂量效应曲线估算得到的剂量值，存在较大的不确定度，尤其进行低剂量估算时更明显；
The uncertainty of estimated dose by dose-effect curve is depending on the dose rate, especially, in the low dose range the influence is remarkable.
结论常用的药效学S型剂量效应曲线拟合的数学模型中，Hill系数无生理学含义。
CONCLUSION the Hill coefficient is considered not any physiological meanings in the mathematics model usually used in fitting pharmacodynamics s dose-effect curve.
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