分化诱导剂对脊索瘤细胞体外粘附、移动和侵袭_医学杂志_健康那些事儿K210.COM Keywords】 Chordoma; Cell line; differentiation inducer; invasion [gap=345]关键词】 脊索瘤;细胞系;分化诱导剂;侵袭性
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...p y sensitizer); (5) 肿瘤血管生成抑制剂 (tumor angiogenesis inhibitor); (6) 分化诱导剂(differentiation inducing agent); (7) 生长因子抑制剂 (growth factor inhibitor); (8) 反义寡核苷酸(antisense oligonucleotide) 。
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CDA-Ⅱis the direct differentiation inducer compared with retinoic acid,interferon,Vitamin D3,methylenediamide,dimethyl sulfoxide and phorbol ester which are indirect differentiation inducer. It exert effects on abnormal methylation enzymes directly.
尿多酸肽是直接作用在异常甲基转移复合酶的分化诱导剂,而目前研究最多的分化诱导剂如维甲酸,干扰素,维生素D3,甲撑二酰胺,二甲基亚砜和佛波酯等,都属于间接分化诱导剂,他们具有一个共同的生物活性,那就是能够有效诱导癌细胞产生寡异核苷酸,产生与尿多酸肽类似的作用。
参考来源 - 尿多酸肽(CDA·2,447,543篇论文数据,部分数据来源于NoteExpress
目的探讨建立高效、快速分化诱导剂筛选模型。
Objective To establish a model for the rapid screening of differentiation-inducing agents.
还对分化诱导剂、拓扑异构酶抑制剂、抗微管药和生物反应调节剂的筛选方法进行了评述。
In addition, the paper reviewed screening methods for differentiation inducers, DNA topoisomerase inhibitors, antimicrotubule drugs and biological response modifiers.
目的:研究肿瘤细胞分化诱导剂尿多酸肽(CDA - II)对人胃癌细胞的体外抑制作用。
Objective: to study the inhibitory effect of Uroacitide (CDA-II) on human gastric cancer cell in vitro.
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