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一些通常在发育胚胎中活跃的基因会被分化细胞(比如皮肤细胞)表达，促使细胞回复到未分化状态。
A handful of genes that are normally active in the developing embryo are expressed in a differentiated cell, such as a skin cell, causing that cell to revert back to its undifferentiated state.
SATB1是一种由于在T细胞的分化和激活中调节相关基因表达起关键作用而广为人知的核内蛋白，它是免疫系统中的关键参与者。
SATB1 is a nuclear protein well known for its crucial role in regulating gene expression during the differentiation and activation of t cells, making it a key player in the immune system.
结论铁合金颗粒使成骨细胞OPG基因表达下降，使破骨细胞分化、活化功能增强，这可能是导致假体松动的骨溶解机制之一。
Conclusion Titanium alloy particles decrease expression of OPG gene in human osteoblasts, and this may contribute to the differentiation of osteoclasts which may lead to the periprosthetic osteolysis.
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