现在分子阵列已经成功应用于蛋白分析、先导化合物的发现等许多领域。
They have already been successfully applied in important areas ranging from protein profiling to the discovery of therapeutic leads.
该文综述了这一领域的主要进展及其在药物研究与开发(如先导化合物的发现和新型诊断与治疗方法的设计)中的应用。
Progress in the field is briefly reviewed and possible application of evolutionary chemistry in drug research and development such as discovery of lead compounds and des…
对核苷类化合物糖环部分的化学改造一直是发现新的具有抗病毒、抗肿瘤或其他生物活性的核苷类先导化合物的重要途径之一。
The chemical modification of sugar moiety in nucleoside or nucleotide is always an important way to discover new lead compounds with anti-viral, anti-tumor and other biological activities.
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