结论苯中毒患者外周血白细胞的DNA复制及损伤修复基因与正常人相比存在差异性表达,为进一步筛选苯中毒生物标志物提供了依据。
Conclusions Some DNA replication, and damage repair genes associated with benzene poisoning show differential expression, which provides the basis for screening biomarkers of benzene poisoning.
目的探讨晚期非小细胞肺癌(NSCLC)组织中DNA修复基因家族成员ERCC1、RRM1和BRCA1的表达及其临床意义。
Objective To investigate the expression of DNA repair gene family members of ERCC1, RRM1 and BRCA1 in tissues of advanced non-small cell lung cancer (NSCLC), and explore its clinical significance.
目的:探讨核苷酸切除修复基因ERCC1在肺癌中的表达及其与多环芳烃(PAH) - DNA加合物的关系。
AIM: To investigate the expression of nucleotide excision repair gene ERCC1 and its relationship with PAH (polycyclic aromatic hydrocarbons) -dna adducts in lung cancer tissues.
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