信号识别颗粒(SRP)在真核细胞中如何定向和转运蛋白质是非常清楚和统一的。
How proteins are targeted and translocated mediated by signal recognition particle (SRP) in eukaryotic cell is very clear and uniform.
CD24-Siglec复合体还可识别另一种内源性危险信号热休克蛋白,但对脂多糖或poly-(dI:dC)这两种外源性危险信号均无反应。
The CD24-Siglec complex also recognizes heat shock proteins, another class of endogenous danger signals, but does not respond to lipopolysaccharide or poly-(dI:dC), two exogenous danger signals.
特异的信号基序不仅包括蛋白激酶可以识别的序列(1),也包括那些能够被磷酸化依赖结合蛋白如14-3-3识别的序列(2)。
Specific signaling motifs include not only sequences that are recognized by protein kinases (1), but also those that are recognized by phosphorylation-dependent binding proteins such as 14-3-3 (2).
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