雌激素替代疗法是传统的治疗，但是因为与中风，栓塞，乳腺癌之间的风险联系医生已经不推荐长期使用雌激素进行治疗。
Estrogen hormone replacement therapy was the traditional treatment, but it is no longer recommended for the long term because of links to stroke, embolism and breast cancer.
她补充到：“但是如果对于WHI发现以及WHIMS试验结果而言，大量传统运用激素替代治疗的随机对照试验将是不道德的。”
However, she added, based on the WHI findings, as well as the WHIMS trial results, a large randomized controlled trial using conventional HRT would be unethical.
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