目的以羟丙甲基纤维素为骨架材料制得灯盏花素缓释片，并对释药机制进行探讨。

OBJECTIVE Breviscapine sustained-release tablets(BST)were formulated with hydroxypropyl-methylcellulose as the matrix material and the release mechanism of the tablets was studied.

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以羟丙甲基纤维素作为主要的缓释辅料，采用正交设计方法优化处方研制成脑络康缓释胶囊。

Hydroxypropyl methylcellulose (HPMC) was used as the main sustained release excipient of Naoluotong sustained release Capsules, and the formula was optimized by the orthogonal experimental design.

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方法 以羟丙甲基纤维素为骨架材料 ，70 %乙醇为粘合剂 ，采用湿法制粒压片 ，以紫外分光光度法测定其在不同释放介质中的释放度。

Methods HPMCK 4M was utilized as matrix, 70% ethanol was employed as a binding agent to obtain wet granules. The dissolution in different mediums were determined by UV specophotography.

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