本文综述了谷胱甘肽及其相关酶系统在肿瘤多药耐药中的作用,介导多药耐药的可能机制以及谷胱甘肽类似物结构与转运活性的关系。
We introduced the effects on MDR, the possible mechanisms of glutathione and related enzymes, as well as the relationship between structure of GSH analogues and the transport activity in this paper.
哺乳动物氨基酸的跨膜运输由多种氨基酸转运载体蛋白介导,其中L型氨基酸转运载体1(LAT1)属于L系统,主要转运大分子支链氨基酸和芳香族中性氨基酸。
L-type amino acid transporter-1 (LAT1) is a member of the sodium-independent amino acid transport system L and transports large branched-chain and aromatic neutral amino acids.
我们假设多药抗药性相关蛋白-1介导的白三烯C4内位-外位转运是致血管系统动脉粥样硬化的重要机制。
We hypothesize that inside-outside transport of leukotriene C4 (LTC4) via MRP1 is a substantial proatherogenic mechanism in the vasculature.
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