水稻突变体与功能基因组学 - 网上读书园地 - 信息资讯 - 专业交流 - 生命科学 免费读书 3)烷化剂,甲基磺酸乙酯( EMS,ethy1 methanesulfonate )、N-甲基-N-亚硝基脲( MNU,methylnitrosourea )烯亚胺、亚硝基乙基尿烷和亚硝基乙基尿;(4)其他种类的诱变剂,亚硝酸和吖啶。 MNU 和 EM
基于8个网页-相关网页
In contrast , N-methyl -N-nitrosourea (MNU )-induced tumors are very similar to human bladder transitional cell carcinomas and are considered to be excellent models of clinical bladder cancer.
由N-甲基-亚硝基脲(MNU)膀胱灌注诱导的膀胱肿瘤与人类膀胱肿瘤发生特点及病理学特征非常相似,可以认为是膀胱肿瘤研究的较理想模型之一。
参考来源 - 经尿道灌注HSV·2,447,543篇论文数据,部分数据来源于NoteExpress
亚硝基脲的抗癌与致癌机理是非常接近的,都能够使DNA碱基发生烷化,进一步形成DNA股间交联。
The anticancer mechanism of nitrosoureas is very similar to the carcinogenic mechanism, both of them can alkylate DNA bases and form DNA cross-linking further.
接种细胞一天后,用不同剂量乙基亚硝基脲(ENU)处理2小时,然后用标准法检查其染色体畸变和SCE率,用细胞计数法测定细胞毒性。
One day after plating, the cells were exposed for 2 h to various doses of ethylnitrosourea (ENU). CAs and SCEs were examined by the standard methods, while CT was determined by cell counts.
目的探讨亚硝基乙基脲(NEU)经胎盘诱发脑肿瘤动物模型的时间和剂量依赖性。
Objective To study time and dose dependence of animal models with brain neoplasms induced transplacentally with N-ethyl-N-nitrosourea (NEU).
应用推荐