目的探讨亚硝基乙基脲(NEU)经胎盘诱发脑肿瘤动物模型的时间和剂量依赖性。
Objective To study time and dose dependence of animal models with brain neoplasms induced transplacentally with N-ethyl-N-nitrosourea (NEU).
接种细胞一天后,用不同剂量乙基亚硝基脲(ENU)处理2小时,然后用标准法检查其染色体畸变和SCE率,用细胞计数法测定细胞毒性。
One day after plating, the cells were exposed for 2 h to various doses of ethylnitrosourea (ENU). CAs and SCEs were examined by the standard methods, while CT was determined by cell counts.
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