目的利用杆状病毒表达载体系统制备重组乙型肝炎病毒核心蛋白。
Objective To produce recombinant HBcAg in insect cells by Baculovirus expression vector system.
对重组乙型肝炎(乙肝) 病毒前S1 抗原(1- 42 )及核心抗原(1- 144 )表达的融合蛋白CS1进行了免疫原性的研究分析,以便为探索HBV治疗性疫苗的研制提供实验依据。
The aim of this study was to express a fusion protein of HBV preS1 Ag(1-42) and HBcAg(1-144) and analyze its immunogenicity for further study of HBV therapeutic vaccine.
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