肾脏器官在低温离体保存过程中,血管内皮细胞和肾小管上皮细胞功能结构的完整性是维持器官功能完整的关键。
During the process of off body kidney low temperature preservation, it is the key proceeding to remain the structure and function integrality of cells in vascular endothelium and tubule epithelium.
背景:钠-葡萄糖协同转运蛋白2(SGLT2)在近端肾小管表达,负责重吸收肾小管液中90%的葡萄糖。
Context: Sodium-glucose cotransporter 2 (SGLT2) expressed in the proximal renal tubules accounts for about 90% of the reabsorption of glucose from tubular fluid.
目的建立尿中性肽内切酶(NEP)检测的ELISA法,明确用ELISA法检测尿nep在诊断肾小管损伤中的意义。
Objective to set up an ELISA method to measure urinary neutral endopeptidase (NEP) and determine its clinical meaning in diagnosing renal tubular injury.
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