阐述了不同类型反流物对食管上皮细胞的损伤，评价在反流性食管炎中基因的突变，以及与食管腺癌的联系。
To review the injury of different reflux content to esophageal epithelial barrier, evaluate the presence of mutation at gene in GERD, and related with esophageal adenocarcinoma.
高脂肪饮食已表明与肥胖有关，而肥胖又是一个众所周知的许多癌症的危险因素，这些癌症包括：绝经后乳腺癌、结肠癌、肾癌以及食管癌。
High-fat diets have been linked to obesity, and obesity is a known risk factor for a number of cancers, including postmenopausal breast, colon, kidney, and esophageal cancers.
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