MMP9均为基质降解酶,可以降解由细胞外基质(Extracelluler Matrices,ECM)与血管基底膜(Basement Membrance,BM)组成的屏障,在肿瘤细胞向瘤灶周围的侵袭性生长中发挥重要作用。
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蛇毒金属蛋白酶是蛇毒主要功能性蛋白质之一,它直接作用于局部组织的毛细血管,影响毛细血管内皮细胞与基底膜之间的相互作用;
Snake venom metalloproteinase is one of the main function proteins in snake venom. It directly affects the interactions between capillary endothelium cells and basement membrane in local tissues.
病理表现为系膜基质增多,肾小球基底膜上皮下透明物质积聚以及毛细血管袢与包氏囊粘连等改变。
The pathological character shows that messegium increased, transparency material of the glomerulus basement membrane epithelium accumulates, capillary and capsular adheres.
富硒枸杞组与宁夏枸杞组在肾小球硬化率,管周毛细血管数,基底膜厚度等指标有显著性差异(P <0 .0 5 )。
The parameters of glomerulus sclerosis rate, the number of peritubular capillary, basement membrane thickness were different between LBL and SLBL groups(P<0.05).
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