由于P-gp与肿瘤多药耐药(Muhidrug Resistance，MDR)有关，后者是指一种药物作用于肿瘤使之产生耐药性后，该肿瘤对未接触过的、结构无关、机制各异的多种抗肿瘤...
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目前的研究发现，有多类细胞色素P 450酶与肿瘤多药耐药的发生密切相关。
In recent years, researches found that there were many kinds of cytochrome P450 enzymes which related to multidrug resistance of tumor.
本文综述了谷胱甘肽及其相关酶系统在肿瘤多药耐药中的作用，介导多药耐药的可能机制以及谷胱甘肽类似物结构与转运活性的关系。
We introduced the effects on MDR, the possible mechanisms of glutathione and related enzymes, as well as the relationship between structure of GSH analogues and the transport activity in this paper.
近年研究发现容积调控性氯通道与肿瘤细胞的增殖、侵袭、迁移、凋亡及多药耐药性等恶性生物学行为有关。
In recent years, it has been realized that volume-regulated chloride channels are closely associated with proliferation, invasion, migration, apoptosis and multi drug resistance of tumor cells.
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