...功能改变;HAPE患者肺组织内皮源性因子的分布;HAPE患者内皮细胞源性因子改变与缺氧性肺动脉高压（Hypoxic pulmonary hypertension,HPH）的关系。
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目的：探讨内皮素- 1 (et - 1)与缺氧性肺动脉高压(HPH)的相互关系。
Purpose To study the effects of Endothelin-1 (ET-1) in hypoxic pulmonary hypertension (HPH) and its relationship with HPH.
作者研究了慢性间断低压缺氧对大鼠肺血管反应性的影响及其与组胺的关系。动物经慢性缺氧后发生慢性肺动脉高压，其肺血管对急性缺氧的反应性降低。
The effect, of chronic intermittent hypobaric hypoxia on pulmonary vascular reactivity to acute hypoxia in. rats and its relationship to histamine have been studied.
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