...人群的HLA遗传多态性分布特征,筛选、鉴定HLA-A、B、DRB1位点新等位基因,并探讨HLA与慢性髓细胞白血病(Chronic myeloid leukemia,CML)发生的相关性。
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“慢性”白血病少有或几乎没有母细胞。与急性白血病相比，“慢性淋巴细胞性白血病”和“慢性髓细胞性白血病”通常进程相对缓慢。
"Chronic" leukemias have few or no blast cells. "chronic lymphocytic leukemia" and "chronic myelogenous leukemia" usually progress slowly compared to acute leukemias.
目的了解细胞程序死亡(PCD)与慢性髓细胞性白血病(CML)急变的关系。
Objective To investigate the association of the programmed cell death (PCD) regulating proteins with the acute transformation of chronic myelogenous leukemia (CML).
须与类白血病相鉴别，可用的检测是粒细胞碱性磷酸酶(LAP)，慢性髓性白血病较低而类白血病反应较高。
A useful test to help distinguish this disease is the leukocyte alkaline phosphatase (LAP) score, which should be low with CML and high with a leukemoid reaction.
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