目的：观察必思添改善慢性阻塞性肺疾病反复下呼吸道感染的疗效。
AIM: To observe the effects of Biostim in prevention and improvation of recurrent lower respiratory tract infection in chronic obstructive pulmonary diseases (COPD).
目的寻找一种快速准确的收集慢性阻塞性肺疾病(COPD)患者下呼吸道痰液的方法，并探讨其安全性。
Objective To evaluate the safety and effectiveness of a sputum collection method in patients with chronic obstructive pulmonary disease (COPD).
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