最近研究出一种抗肿瘤生物制剂为Apoptin(细胞凋亡素),Apoptin是由鸡贫血病毒编码的一种小分子质量蛋白,它以非p53依赖性途径诱导不同类型人肿瘤细胞的凋亡,不受Bcl-2的抑制作用影响...
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在一种被称为凋亡(Apoptosis,凋亡是细胞死亡的机制之一)的过程中,辣椒素可以使癌细胞进行自我破坏,但是却不会影响到其它正常的胰腺细胞。
The compound caused the cancer cells to self-destruct in a process called apoptosis, while not affecting normal pancreatic cells.
同样,在卵巢癌小鼠模型中,抑制应激和相关的去甲肾上腺素和肾上腺素增加可防止肿瘤细胞发生失巢凋亡,从而促进肿瘤生长。
Similarly, in a mouse model of ovarian cancer, restraint stress and the associated increases in norepinephrine and epinephrine protected the tumor cells from anoikis and promoted their growth.
在这项研究中,人类卵巢癌细胞系暴露到应激激素去甲肾上腺素或肾上腺素任何一种都能保护它们免疫失巢凋亡。
In the study, exposure of human ovarian cancer cells lines to either of the stress hormones norepinephrine or epinephrine protected them from anoikis.
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