由于颌面部、牙齿和骨骼发育与虹膜的发育均来源于相同胚叶,故认为中胚叶,尤其是神经胚细胞(Neural crest cell)发育异常是该病的组织学原因。该理论已经被广泛接受,而对于Neural crest cell异常如何导致组织形态学异常,存在不同的学说。
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神经胚细胞瘤 neuroblastoma
神经管胚细胞 medulloblast
胚胎神经干细胞 embryonic neural stem cells ; embryo neural stem cell ; fetus neural stem cells ; neural stem cell
多形神经胶胚细胞瘤 multiform glioblastoma ; glioblastoma mutiforme
人胚神经干细胞 human neural stem cells ; HNSC
神经管胚细胞瘤 medultoblastoma
胚神经干细胞 neural stem cell ; NSC
建立人胚神经干细胞 human Neural Stem Cells ; HNSC
研究者们利用小鼠晶胚来培育脑组织,并且设定了一种环境,在此环境下,脑组织会逐渐流失左旋多巴胺神经细胞,这与帕金逊症的症状非常相似。
Using tissue from mouse embryos, researchers prepared brain cultures using conditions that favor the slowly progressing loss of dopamine neurons, a hallmark of the disease.
方法将鼠胚皮质神经元细胞种在PLGA生物膜支架上,用自制的神经轴突延长装置对其延长。
Methods the rat embryo cortical neuronal cells were cultured after they were seeded on PLGA membrane scaffolds, and elongated with the self-made neuro-axon extending device.
目的从大胚龄人胚脑中分离培养并鉴定神经干细胞。
Objective To isolate and culture human neural stem cells from elder embryonic brain.
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