目的介绍在遗传流行病学病例对照研究中,应用多因子降维法(MDR)分析基因-基因交互作用。
Objective To introduce the application of Multifactor Dimensionality Reduction (MDR) method for detecting gene-gene interactions in genetic case-control studies.
数年前,他提炼出一种技术,可以将基因网络“毛团”——对基因交互作用密集纠结的描绘——转化成分层图。
Several years ago, he refined a technique for turning gene-network "hairballs" - densely tangled depictions of gene interaction - into hierarchical maps.
对于基因数据,则采用回归树分析基因与基因之间、基因与环境之间的交互作用。
For analysis of genomic data, regression tree approaches to the analysis of interactions between genes and between genes and the environment will be used.
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