Having been used as the gene therapy vectors many years,Helper-dependent adenoviral vector (HDAd) steppes later in the vaccines researches. Todate, there are still no reports on HDAd used as gene delivery system aiming atmucosal immunity in vaccines investigation.
辅助病毒依赖型腺病毒载体(helper-dependent adenoviral vector,HDAd)主要用于基因治疗研究,作为疫苗载体的研究起步较晚,尚没有作为黏膜基因释放系统用于疫苗研究的报道。
参考来源 - 可表达人呼吸道合胞病毒融合蛋白的辅助病毒依赖型腺病毒载体的构建与制备·2,447,543篇论文数据,部分数据来源于NoteExpress
载体或基因释放的骨形态发生蛋白2可有效修复骨缺损。
Bone morphogenetic protein-2 released from carrier or gene could repair bone defect effectively.
非病毒基因载体主要有脂质体、人工合成聚合物载体、天然聚合物载体、局部基因释放载体等。
Nonviral gene carriers include liposomes, synthetic polymeric vectors, natural polymeric vectors, local gene delivery vectors and so on.
英格汉姆声称,一种普通土壤细菌的转基因版本如果被释放到野外,可能会传播并摧毁植物。
Ingham claimed that a GM version of a common soil bacterium could spread and destroy plants if released into the wild.
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