Acccrding to the characteristics of these reactions, acylation and nitration, hydrolysis and deamination can be combined respectively so that the synthetic procedure could be reduced to three steps instead of five In this paper.
本文将其中的酰化、硝化合并成一步,去酰基和重氮化去氨基合并成一步,两个“一锅化”法使得原来五步的反应减少为三步。
参考来源 - 3,5·2,447,543篇论文数据,部分数据来源于NoteExpress
它依赖于用 亚硫酸氢钠处理后,非甲基化的 胞嘧啶选择性的去氨基为 尿嘧啶,通常接着所选的靶向区域的PCR扩增。
It relies upon the selective deamination of unmethylated cytosine to uracil after treatment with sodium bisulphite, usually followed by PCR amplification of the chosen target region.
“其他剂型的去氨基精加压,在存在水中毒引起钠失衡危险性的患者中应用应谨慎”,食品与药品管理局(FDA)的官员说。
Other forms of the drug "should be used cautiously" in patients at risk of sodium imbalances that can be caused by over-hydration, the FDA said.
王博士已经成功的让大肠杆菌(遗传学家的常用工作菌种)中的一个密码子重新分配去编码一个非自然氨基酸。
Dr Wang has managed to reassign one of the stop codons in E. coli, the bacterial workhorse of geneticists, to recognise an unnatural amino acid.
应用推荐