从0相到3相复极竣事的时间叫做动作电位时间(action potential duration,apd),从0相到3相中复极化到-60mv的时辰(注重不是到3相纯粹复极竣事),此时间段内纵然赐与很强非常刺...
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从0相到3相复极竣事的时间叫做动作电位时间(action potential duration,apd),从0相到3相中复极化到-60mv的时辰(注重不是到3相纯粹复极竣事),此时间段内纵然赐与很强非常刺...
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(2)KCNQ1作用机制: 基因突变引起IKs的α亚单位功能受损,IKs钾外流量显着减少,从而延长动作电位时间(Action period duration, APD),心电图上表现为QTc延长和尖端扭转性室性心动过速,导致LQTS[1]。
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为动作电位时间 action potential duration ; APD
动作电位时间间隔 ISI
从而延长动作电位时间 Action period duration
动作电位持续时间 action potential duration ; APD
结论丹参酮能够在抗心肌肥厚的同时通过减少钙内流、缩短动作电位时间,起到预防心律失常的作用。
ConclusionTanshinone not only reverses the myocardial hypertrophy, but also reduces calcium influx and shorten action potential duration which are beneficial to prevent arrhythmia.
方法:记录蟾蜍坐骨神经干动作电位和腓肠肌收缩曲线,测定低位运动中枢、神经-肌接头和骨骼肌出现疲劳的时间并加以比较。
Methods: By recording the action potential of sciatic trunk and contract curve of sural muscle of hoptoad, and checking the time of fatigue in nerve center, neuro-muscular junction and muscle.
方法:记录蟾蜍坐骨神经干动作电位和腓肠肌收缩曲线,测定低位运动中枢、神经肌接头、骨骼肌出现疲劳的时间并加以比较。
Methods: By recording the action potential of sciatic trunk and contract curve of sural muscle of hoptoad, and measuring the time of fatigue in nerve centre, neuro-muscular junction and muscle.
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