当糖皮质激素和海马体中的受体结合时，激活了那些阻止这种激素合成的基因。

When glucocorticoid binds to its receptor in the hippocampus, that activates the expression of genes which dampen further synthesis of the hormone.

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例如，后代身上出现的一种称为过氧化物酶体增殖物激活型受体 (Ppara)的基因对调节胆固醇和脂类在肝脏中进行转换起着至关重要的作用。

One gene that changed in offspring, for example — known as Ppara — is essential in cholesterol management and the liver's role in converting lipids.

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化疗药物联合过氧化物酶体增殖物激活受体(PPAR)的配体能够协同抑制肺细胞癌及卵巢癌细胞。

Chemotherapy given in combination with ligands for the peroxisome proliferator-activated receptor - (PPAR) synergistically inhibits the growth of lung and ovarian cancer cell lines.

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This is, maybe, the strangest because the ligand that stimulates the receptor is produced by the cell itself; so sometimes cells make signals that they receive.

它可能是最奇特的,因为激活受体的配体,是由细胞自身产生的,有时细胞产生让自己接受的信号

耶鲁公开课 - 生物医学工程探索课程节选

Much of the work that pharmaceutical companies do in terms of searching for drugs is searching for new ligands that activate receptors and create biological responses inside cells.

很多制药公司新药筛选工作的主要内容,就是寻找能够激活受体的,新型配体,并在细胞内部产生某种生物学效应

耶鲁公开课 - 生物医学工程探索课程节选

So, these are receptors, for example, that bind the ligand and then liberate an enzyme which promotes some sort of reaction inside the cell, often it's kinases but doesn't have to be.

例如,这里是受体,与配体相结合,激活一种酶,这种酶能够催化细胞内的某些反应,这些酶通常都是激酶,但不全是

耶鲁公开课 - 生物医学工程探索课程节选