本文综述了药物基因组学的基本概念、高血压病和抗高血压药物反应异质性、与药物新陈代谢相关的基因、个体化治疗等方面的应用情况。
This review includes basic concepts of pharmacogenomics, heterogeneity of hypertension and antihypertensive drug responses, genes associate with drug metabolism, and individualized drug therapy.
本发明的药物组合物用于治疗和预防血容量不足,能够在 大剂量输液进行扩容治疗时避免高氯代谢性酸中毒的风险。
The medicine composition is used for preventing and treating hypovolemia and may be used in great dosage infusion without risk of hyperchloremic metabolic acidosis.
因此,通过对各种糖代谢通路进行有针对性的干预,有望开发出新型治疗药物。
Hence it is hopeful to exploit new therapeutic drugs by pharmacological interference glycometabolism pathway.
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