...的关键蛋白不断被发现,而且不断转化到临床应用中来, 许多小分子蛋白质的单克隆抗体,如表皮生长因子受体抑制剂(EGFR inhibitor),C225, h-R3, 酪氨酸磷酸化激酶抑制剂如Irresa;等等,这些小分子 物质可以定向,高效的作用于某一个环节,因此也称之为靶向治疗...
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表皮生长因子受体抑制剂在胰腺癌治疗中的作用 关键词:表皮生长因子受体;胰腺癌;EGFR抑制剂 [gap=734]Key words:EGFR;Pancreatic cancer;EGFR inhibitors
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EGFR tyrosine kinase inhibitor 抑制剂 ; 酪氨酸激酶抑制剂
Objective As EGFR inhibitor, Cetuximab has been widely used in several solid tumors, and has perfect therapeutic effect and security.
目的作为EGFR抑制剂,西妥昔单抗在多种实体瘤中应用日益广泛,显示出良好的疗效和安全性。
With the advancement of the study of molecular biology, the research of the molecular targeted drugs such as EGFR inhibitor and VEGF inhibitor, become one of the hot spots.
随着分子生物学研究的进展,表皮生长因子受体抑制剂、血管内皮生长因子抑制剂等分子靶向药物的研究成为热点之一。
A recent clinical trial using an EGFR inhibitor found that patients whose tumors expressed high levels of phosphorylated - or chemically altered - Akt did not respond to treatment, Kwatra said.
最近一项使用表皮生长因子受体抑制剂的临床试验发现,患者的肿瘤细胞表达磷酸化或化学转化水平很高- Akt对这种疗法没有反应“Kwatra博士说。”
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